Bayer: Science For A Better Life - research

Search for active substances to combat serious cardiovascular disease

Help for weak hearts

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Dr. Ulrich Nielsch analyses the genes of the cells. The background shows the graphic evaluation of a gene chip experiment. Each dot corresponds to an individual gene. The colors show the strength of genetic activity in each case.

Damage suffered by the heart muscle as a result of cardiovascular disease often represents the start of a vicious cycle: the weaker the heart muscle becomes, the harder the body expects it to work. Although this pressure to perform can be minimized by drug products, damage to the heart continues to progress. Employees of the Institute for Target Research at Bayer HealthCare are therefore searching for a target for an active substance designed to protect the heart muscle.

Genes provide clues

The search began with tests on the heart tissue of patients with heart failure. The researchers identified proteins that serve as targets for new active substances.

Read the following article to find out more about this research and what progress is being made in the development of a new medicine to treat heart failure.

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