Edition 22, 2010
Targeted therapy of bone metastasis

Fighting tumors with alpha radiation

  • Deadly internal danger: prostate carcinoma is one of the forms of cancer that spread the most bone metastases throughout the body. If the tumor is detected at an early stage – while it is still confined to the prostate gland – surgery can provide a cure.
  • In screening tests, Dr. Martin Pelster (right) checks certain indicators that may show that the disease is present.
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Deadly internal danger: prostate carcinoma is one of the forms of cancer that spread the most bone metastases throughout the body. If the tumor is detected at an early stage – while it is still confined to the prostate gland – surgery can provide a cure.

Prostate cancer can often be successfully treated if it is diagnosed at an early stage. Once the disease has formed daughter tumors in the bones, however, it becomes life-threatening. The standard treatment at this advanced stage is chemotherapy. Doctors also employ radiation and hormonal treatments. However, many active ingredients become ineffective because most carcinomas develop resistance with time.

Faster to the site of action
Scientists at Bayer HealthCare are now testing a new drug product that is designed to target bone metastasis: Alpharadin, an alpha radiation substance, can be easily administered intravenously and finds its way into the skeleton within 10 minutes. This means that other organs and tissues are only exposed to the radiation for a short time.

To find out whom the new active ingredient can help, read on here:

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