Edition 22, 2010
Targeted transport of active ingredients with antibodies

Double whammy

  • Fight against cancer: Bayer HealthCare is constantly on the lookout for new ways to target cancer cells, for example in the lungs, more selectively with drugs.
  • Scientists Dr. Berthold Boedeker (left) and Dr. Hans-Georg Lerchen are working on a solution with antibodies that transport an active ingredient directly to the cancer cells and thus selectively target the tumor.
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Fight against cancer: Bayer HealthCare is constantly on the lookout for new ways to target cancer cells, for example in the lungs, more selectively with drugs.

Chemotherapy and radiation therapy are the standard treatments in the battle against cancer. But substances that help to destroy proliferating tumor cells on the one hand can also damage healthy tissue on the other. They also frequently lead to side effects such as a compromized immune system, hair loss, nausea and vomiting. Medical scientists around the world are therefore searching for new ways to, for example, transport drug products more directly to the site of action.

Trojan horse in the battle against cancer
Scientists at Bayer HealthCare are now working on a new therapeutic approach: they are coupling highly effective cytotoxins to special protein molecules called antibodies. These compounds known as immunoconjugates or antibody drugs are intended to transport the active ingredient directly to the cancer cell. Once inside, the toxin is released to kill the cancer cell.

To find out more about how these modern Trojan horses are helping in the battle against cancer, read on here:

Last updated: December 12, 2013  Copyright © Bayer AG
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